We have unceasingly strived to realize our corporate philosophy of always making a contribution to human health.
Kyorin will continue to take on challenges and will evolve to become a company supporting healthy lifestyles through our business in the treatment and prevention of disease and the maintenance and promotion of good health.
Company history
Product history
1920~
1923
Toyo Shinyaku Sha, the predecessor of KYORIN Pharmaceutical Co., Ltd., was founded.

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1931
Kyorin Chemical Laboratory was established.
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1940
Kyorin Chemical Laboratory was renamed KYORIN Pharmaceutical Co., Ltd., and Kyorin Yakuhin Co., Ltd. was organized as an independent marketing division.
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1947
The Okaya Plant was started

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1950~
1957
The medical journal bulletin “Doctor Salon” was started.

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1961
Behyd, a diuretic and antihypertensive agent, was launched.

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1962
Kyorin Chemical Laboratory (later Technical Center of Development) was established.

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1965
The Head Office was completed in Kanda Surugadai.

1965
KYORIN AP-2, an analgesic, was launched.
Deamelin-S, an oral hypoglycemic agent, was launched.

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1967
The Nogi Plant was opened.
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1971
Cholexamin, a lipid metabolism and peripheral circulation improving agent, was launched.

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1974
Hespander, a plasma substitute and extracorporeal circulation flow improver, was launched.

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1977
Central Research Laboratories were opened.

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1980~
1980
Norfloxacin (NFLX), an antibacterial agent, was licensed to Merck & Co. (U.S.A.).
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1981
Mucodyne, a mucoregulant, was launched.

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1984
Baccidal (NFLX), a broadspectrum oral antibacterial agent, was launched.

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1989
Ketas, for bronchial asthma and cerebrovascular disorders, was launched.
Baccidal Eyedrops, a broadspectrum ophthalmic antibacterial agent, was launched.

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1992
KYORIN Pharmaceutical Co., Ltd. and Kyorin Yakuhin Co., Ltd. were merged, and the new KYORIN Pharmaceutical Co., Ltd. was founded.
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1993
Megalocin (FLRX), a long-acting new quinolone agent, was launched.

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1995
The Noshiro Plant was opened.

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1996
A joint venture, Nisshin KYORIN Pharmaceutical Co., Ltd., was established with Kyorin’s capital participation.
The Research Center (now the WATARASE Research Center) was founded.

1996
Pentasa, a treatment for ulcerative colitis and Crohn’s disease, was launched.
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1996
Gatifloxacin (GFLX) was licensed to Bristol-Myers Squibb (U.S.A.).
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1998
Milton, an effervescent disinfectant business, was acquired from P&G.
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1999
Listed on the Tokyo Stock Exchange, Second Section.
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2000
Listed on the Tokyo Stock Exchange, First Section.
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2000~
2000
Gatifloxacin eyedrops was licensed to Allergan (U.S.A.).
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2001
A subsidiary company, Kyorin USA, Inc. (U.S.A.), was established.
2001
Kipres, the leukotriene receptor antagonist and bronchial asthma treatment medicine, was launched.

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2002
A subsidiary company, Kyorin Europe GmbH (Germany), was established.
2002
Gatiflo (GFLX), a broad-spectrum, oral antibacterial agent, was launched.

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2004
ActivX Biosciences, Inc. (U.S.A.) became a wholly owned subsidiary.

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2005
The stock of Toyo Pharma Co., Ltd. (present KYORIN Rimedio Co., Ltd.) was acquired, making it into a subsidiary company.
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2006
The Nogi Plant was closed.
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2006
The Kyorin Group shifts to a holding company structure through a share exchange with KYORIN Co., Ltd.
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2007
Uritos Tablets 0.1 mg, an overactive bladder drug, was launched.

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2008
KYORIN Pharmaceutical merged with Nissin Kyorin Pharmaceutical.
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2010
KYORIN Co., Ltd. changed its name to KYORIN Holdings, Inc.
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2010~
2012
Acquisition (conversion into subsidiary) of the Shiga Plant of MSD K.K. and established KYORIN Pharmaceutical Facilities Co., Ltd.
2012
RUBYSTA, a multi-purpose disinfectant cleaner, was launched.

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2013
Head office moved to Ochanomizu sola city in Kanda Surugadai.
2013
Flutiform, a combination drug for asthma treatment, was launched.

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2015
Establishment of the WATARASE Research Center of KYORIN Pharmaceutical Co., Ltd. through consolidation of the Drug Discovery Center (the former Central Research Laboratories) and the R&D Center (the former Research Center).

2015
Eklira Genuair, a treatment for COPD, was launched.
FPR2 agonist program was licensed to Bristol-Myers Squibb Company (U.S.A.)

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2016
The Okaya Plant was closed
2016
Montelukast tablets 10mg, 5mg「KM」, the leukotriene receptor antagonist and bronchial asthma treatment medicine, was launched.
DESALEX Tablets 5mg a treatment of allergic diseases drug was launched

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2017
KYORIN Rimedio Co., Ltd.’s Takaoka Pharmaceutical Technology Innovation Center was established.
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2018
New manufacturing subsidiary, KYORIN Pharmaceutical Group Facilities Co., Ltd. (head office: Tokyo), commences operations.
2018
Beova Tablets 50mg a treatment of OAB drug was launched

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2019
GeneSoC®, a microchannel-based genetic measurement device, was launched.

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2020
KYORIN Pharmaceutical Group Facilities Co., Ltd. and KYORIN Medical Supply Co., Ltd. merge.
2020
Lasvic Tablets 75mg an oral quinolone antibacterial agent was launched

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2021
Lasvic Intravenous Drip Infusion Kit 150mg an injectable new quinolone antibacterial agent was launched

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Zymso Intravesical Solution 50%, an interstitial cystitis treatmet was launched

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GeneSoC® mini was launched.

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2022
Lyfnua® Tablets 45mg Selective P2X3 receptor antagonist/Refractory chronic cough was launched

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